/* ==========================================================================
   Landau Lab — research-theme pages (synaptic imaging, stimulation,
   neuroinflammation). Loaded after site.css. Components: theme rail,
   hero schematics, "two views" cards, self-running demos, findings board,
   papers list and the four-theme band.
   ========================================================================== */

:root{--sand-l:#d2ae72;--petrol-l:#7fb9bd}

/* ---------- theme rail (where am I among the four themes) ---------- */
.theme-rail{margin-top:2rem;display:grid;grid-template-columns:repeat(4,minmax(0,1fr));gap:1px;background:var(--line);border:1px solid var(--line);border-radius:var(--radius);overflow:hidden;max-width:40rem}
.theme-rail a{background:var(--paper-2);padding:.55rem .7rem .6rem;display:flex;flex-direction:column;gap:.1rem;font-size:.8rem;line-height:1.25;color:var(--muted);transition:background .2s ease,color .2s ease}
.theme-rail a b{font-family:var(--mono);font-size:.62rem;font-weight:500;letter-spacing:.14em;color:var(--accent)}
.theme-rail a:hover{background:var(--card);color:var(--ink)}
.theme-rail a[aria-current="page"]{background:var(--card);color:var(--ink);box-shadow:inset 0 -2px 0 var(--accent)}
@media (max-width:560px){.theme-rail{grid-template-columns:repeat(2,minmax(0,1fr))}}

/* ---------- hero schematic ---------- */
.hero-svg{position:relative}
.hero-svg svg{width:100%;height:auto;display:block;overflow:visible}
.hero-svg text{font-family:var(--mono);font-size:10px;letter-spacing:.1em;fill:var(--muted)}
.hero-svg .serif{font-family:var(--serif);font-size:17px;letter-spacing:0;fill:var(--ink)}
.schem-flag{position:absolute;right:0;top:0;font-family:var(--mono);font-size:.6rem;letter-spacing:.12em;text-transform:uppercase;color:#7d5f2f;border:1px solid var(--sand-line);border-radius:999px;padding:.12rem .5rem;background:var(--paper)}
@media (prefers-reduced-motion:reduce){.hero-svg *{animation:none!important}}

/* ---------- lede figures, statements ---------- */
.keyline{margin-top:1.8rem;padding:1.1rem 1.3rem;border:1px solid var(--accent-line);background:var(--accent-soft);border-radius:var(--radius);max-width:var(--measure);display:grid;grid-template-columns:auto 1fr;gap:.9rem;align-items:start}
.keyline .ic{width:30px;height:30px;border-radius:50%;border:1px solid var(--accent);display:flex;align-items:center;justify-content:center;font-family:var(--serif);font-size:1rem;color:var(--accent-deep);margin-top:.1rem}
.keyline p{font-family:var(--serif);font-size:1.12rem;line-height:1.5;color:var(--ink);font-weight:400}
.keyline p small{display:block;font-family:var(--sans);font-size:.86rem;color:var(--ink-soft);margin-top:.35rem;line-height:1.55}

/* figure with burned-in-style HTML labels (e.g. Rossi Fig. 2) */
.fig-labels{display:grid;grid-template-columns:repeat(3,1fr);margin-top:.5rem;font-family:var(--mono);font-size:.62rem;letter-spacing:.12em;text-transform:uppercase;color:var(--muted);text-align:center}
@media (max-width:520px){.fig-labels{font-size:.54rem;letter-spacing:.06em}}

/* ---------- two views (PET / autoradiography) ---------- */
.views .cell .tag-k{font-family:var(--mono);font-size:.62rem;letter-spacing:.16em;text-transform:uppercase;color:var(--accent)}
.views .cell h3{font-size:1.3rem}
.views .cell .tr{font-family:var(--mono);font-size:.78rem;color:var(--ink-soft)}
.views .cell ul{margin:.2rem 0 0;padding:0;list-style:none;display:grid;gap:.45rem}
.views .cell li{position:relative;padding-left:1.1rem;color:var(--ink-soft);font-size:.93rem;line-height:1.5}
.views .cell li::before{content:"";position:absolute;left:0;top:.62em;width:.45rem;height:1px;background:var(--accent)}
.views .cell li.no::before{background:var(--sand)}
.views .cell a.more{margin-top:auto;font-family:var(--mono);font-size:.72rem;color:var(--accent-deep);border-bottom:1px solid var(--accent-line);align-self:flex-start}

/* ---------- self-running demo card ---------- */
.demo{margin-top:2.2rem;background:var(--card);border:1px solid var(--line);border-radius:var(--radius);box-shadow:0 18px 40px -28px rgba(27,26,22,.18)}
.demo-top{display:flex;flex-wrap:wrap;justify-content:space-between;align-items:center;gap:.5rem 1rem;padding:.85rem 1.1rem;border-bottom:1px solid var(--line)}
.demo-top .k{font-family:var(--mono);font-size:.64rem;letter-spacing:.16em;text-transform:uppercase;color:var(--muted)}
.demo-top .k b{color:var(--ink);font-weight:500}
.demo-flag{display:none;font-family:var(--mono);font-size:.64rem;letter-spacing:.06em;color:#7d5f2f}
.demo-flag::before{content:"";display:inline-block;width:5px;height:5px;margin:0 .45rem .1rem 0;border-radius:50%;background:var(--sand);animation:tping 2.6s ease-out infinite}
.demo.is-auto .demo-flag{display:inline}
@keyframes tping{0%{box-shadow:0 0 0 0 rgba(210,174,114,.5)}70%,100%{box-shadow:0 0 0 7px rgba(210,174,114,0)}}
.demo-stage{padding:clamp(.8rem,2vw,1.3rem)}
.demo-controls{display:flex;flex-wrap:wrap;align-items:center;gap:.5rem;padding:.9rem 1.1rem;border-top:1px solid var(--line)}
.demo-msg{padding:1rem 1.1rem;border-top:1px solid var(--line);background:var(--paper-2);font-size:.94rem;line-height:1.55;color:var(--ink-soft);border-radius:0 0 var(--radius) var(--radius);min-height:5.2rem}
.demo-msg b{color:var(--ink);font-weight:600}
.demo .pill{display:inline-flex;align-items:center;gap:.5rem;min-height:36px;padding:.38rem .9rem .38rem .72rem;border-radius:999px;cursor:pointer;
  border:1px solid var(--line-strong);background:var(--card);color:var(--ink);font-family:var(--mono);font-size:.7rem;font-weight:500;letter-spacing:.04em;
  transition:border-color .2s ease,background .2s ease,color .2s ease,transform .15s ease}
.demo .pill i{flex:none;width:8px;height:8px;border-radius:50%;border:1px solid currentColor;transition:background .2s ease}
.demo .pill:hover{border-color:var(--accent)}
.demo .pill:active{transform:scale(.97)}
.demo .pill[aria-pressed="true"]{background:var(--ink);border-color:var(--ink);color:var(--paper)}
.demo .pill[aria-pressed="true"] i{background:var(--sand-l);border-color:var(--sand-l)}
.demo .pill small{font-weight:400;color:var(--muted)}
.demo .pill[aria-pressed="true"] small{color:rgba(245,242,236,.65)}
.demo .replay{margin-left:auto;font-family:var(--mono);font-size:.68rem;letter-spacing:.06em;color:var(--muted);background:none;border:0;border-bottom:1px solid var(--line-strong);padding:.2rem 0;cursor:pointer}
.demo .replay:hover{color:var(--accent-deep);border-bottom-color:var(--accent)}
@media (max-width:520px){.demo .pill{font-size:.64rem;padding:.34rem .7rem .34rem .6rem}.demo .pill small{display:none}.demo .replay{margin-left:0}}
.demo-cap{padding:.9rem 1.1rem 1.1rem;border-top:1px solid var(--line);font-size:.84rem;line-height:1.55;color:var(--muted)}
.demo-cap .credit{display:block;margin-top:.4rem;font-family:var(--mono);font-size:.66rem;letter-spacing:.02em}
.demo-cap .credit a,.demo-cap a{border-bottom:1px solid var(--line-strong)}

/* block stepper (synaptic imaging) */
.block-stage{display:grid;grid-template-columns:repeat(3,minmax(0,1fr)) minmax(0,.34fr);gap:clamp(.3rem,1vw,.6rem);background:#000;border-radius:3px;padding:clamp(.3rem,1vw,.6rem)}
.block-slot{position:relative;aspect-ratio:460/750;background:#000;overflow:hidden;border-radius:2px}
.block-slot img{position:absolute;inset:0;width:100%;height:100%;object-fit:contain;transition:opacity .7s ease}
.block-slot .ph{position:absolute;inset:0;display:flex;flex-direction:column;align-items:center;justify-content:center;gap:.4rem;padding:.4rem;text-align:center;
  border:1px dashed rgba(245,242,236,.28);border-radius:2px;color:rgba(245,242,236,.62);font-family:var(--mono);font-size:.62rem;letter-spacing:.08em;line-height:1.35;transition:opacity .5s ease}
.block-slot .ph b{font-size:1.1rem;font-weight:400;color:var(--sand-l)}
.block-slot:not(.on) img{opacity:0}
.block-slot.on .ph{opacity:0}
.block-scale{aspect-ratio:151/750;background:#fff;border-radius:2px;overflow:hidden;align-self:start}
.block-scale img{width:100%;height:100%;object-fit:contain}
@media (max-width:520px){.block-slot .ph{font-size:.5rem;letter-spacing:.02em}}

/* route explorer (stimulation) */
.explore{display:grid;grid-template-columns:minmax(0,.9fr) minmax(0,1.1fr);gap:0}
@media (max-width:860px){.explore{grid-template-columns:1fr}}
.explore-fig{padding:clamp(.8rem,2vw,1.3rem);border-right:1px solid var(--line);background:var(--paper-2)}
@media (max-width:860px){.explore-fig{border-right:0;border-bottom:1px solid var(--line)}}
.explore-fig svg{width:100%;height:auto;display:block;max-width:420px;margin-inline:auto}
.explore-fig svg text{font-family:var(--mono);font-size:9.5px;letter-spacing:.08em;fill:var(--muted)}
.explore-fig .route-path{fill:none;stroke:var(--line-strong);stroke-width:2;stroke-linecap:round;transition:stroke .4s ease}
.explore-fig .route-pulse{fill:none;stroke:var(--sand);stroke-width:2.6;stroke-linecap:round;stroke-dasharray:3 22;opacity:0;transition:opacity .4s ease}
.explore-fig .dev{fill:var(--card);stroke:var(--line-strong);stroke-width:1.3;transition:fill .4s ease,stroke .4s ease}
.explore-fig .lbl{transition:fill .4s ease}
.explore-fig [data-r].on .route-path{stroke:var(--accent)}
.explore-fig [data-r].on .route-pulse{opacity:1;animation:tpulse 1.4s linear infinite}
.explore-fig [data-r].on .dev{fill:var(--sand-l);stroke:#7d5f2f}
.explore-fig [data-r].on .lbl{fill:var(--ink)}
.explore-fig .ripple{fill:none;stroke:var(--accent);stroke-width:1;opacity:0}
.explore-fig [data-r].on .ripple{animation:tripple 2.4s ease-out infinite}
.explore-fig [data-r].on .ripple.r2{animation-delay:.8s}
.explore-fig [data-r].on .ripple.r3{animation-delay:1.6s}
@keyframes tpulse{to{stroke-dashoffset:-50}}
@keyframes tripple{0%{opacity:.55;transform:scale(.4)}100%{opacity:0;transform:scale(1.5)}}
.explore-fig .ripple{transform-box:fill-box;transform-origin:center}
@media (prefers-reduced-motion:reduce){.explore-fig [data-r].on .route-pulse,.explore-fig [data-r].on .ripple{animation:none}.explore-fig [data-r].on .ripple{opacity:.25}}
.explore-panel{padding:1.1rem 1.2rem 1.2rem;display:flex;flex-direction:column;gap:.8rem}
.explore-panel[hidden]{display:none}
.explore-panel .k{font-family:var(--mono);font-size:.62rem;letter-spacing:.16em;text-transform:uppercase;color:var(--accent)}
.explore-panel h3{font-size:1.35rem;line-height:1.25}
.explore-panel .how{font-size:.93rem;color:var(--ink-soft)}
.explore-panel ol{list-style:none;margin:0;padding:0;border-top:1px solid var(--line)}
.explore-panel li{padding:.75rem 0;border-bottom:1px solid var(--line);font-size:.92rem;line-height:1.5;color:var(--ink-soft)}
.explore-panel li .m{display:flex;flex-wrap:wrap;gap:.3rem .5rem;margin-bottom:.3rem;font-family:var(--mono);font-size:.62rem;letter-spacing:.06em;text-transform:uppercase;color:var(--muted)}
.explore-panel li .m .tr{color:var(--accent-deep);text-transform:none;letter-spacing:.02em;font-size:.7rem}
.explore-panel li .c{display:block;margin-top:.25rem;font-family:var(--mono);font-size:.66rem;color:var(--muted)}
.explore-panel li .c a{border-bottom:1px solid var(--line-strong)}
.explore-panel li .c a:hover{border-bottom-color:var(--accent)}

/* glia stepper (neuroinflammation) */
.quad{position:relative;max-width:470px;margin-inline:auto}
.quad img{display:block;width:100%;height:auto}
.quad .hl{position:absolute;border:2px solid var(--sand);border-radius:3px;box-shadow:0 0 0 9999px rgba(245,242,236,.0);opacity:0;transition:opacity .45s ease}
.quad .hl.on{opacity:1}
.quad .dim{position:absolute;background:rgba(250,248,243,.72);transition:opacity .45s ease;pointer-events:none}
.quad .dim.off{opacity:0}
.quad .hl span{position:absolute;left:0;top:0;border-radius:0 0 3px 0!important;font-family:var(--mono);font-size:.6rem;letter-spacing:.1em;text-transform:uppercase;background:var(--sand);color:#fff;border-radius:3px 3px 0 0;padding:.14rem .45rem;white-space:nowrap}

/* ---------- findings board ---------- */
.findings{margin-top:2rem;display:grid;gap:2rem}
.fgroup h3{font-family:var(--mono);font-size:.68rem;font-weight:500;letter-spacing:.18em;text-transform:uppercase;color:var(--muted);display:flex;align-items:center;gap:.7rem}
.fgroup h3::after{content:"";flex:1;height:1px;background:var(--line)}
.fgroup ol{list-style:none;margin:.8rem 0 0;padding:0;display:grid;gap:.6rem}
.f{display:grid;grid-template-columns:2.4rem minmax(0,1fr);gap:.9rem;align-items:start;background:var(--card);border:1px solid var(--line);border-radius:var(--radius);padding:.95rem 1.1rem .95rem .95rem}
.f .dir{width:2.4rem;height:2.4rem;border-radius:50%;display:flex;flex-direction:column;align-items:center;justify-content:center;font-family:var(--serif);font-size:1.15rem;line-height:1;border:1px solid var(--line-strong);color:var(--ink-soft);background:var(--paper-2)}
.f .dir small{font-family:var(--mono);font-size:.42rem;letter-spacing:.08em;text-transform:uppercase;margin-top:.12rem}
.f .dir.up{border-color:var(--sand-line);background:var(--sand-soft);color:#7d5f2f}
.f .dir.down{border-color:var(--accent-line);background:var(--accent-soft);color:var(--accent-deep)}
.f .dir.same{border-style:dashed}
.f .t{font-size:.95rem;line-height:1.55;color:var(--ink-soft)}
.f .t b{color:var(--ink);font-weight:600}
.f .meta{display:flex;flex-wrap:wrap;align-items:center;gap:.35rem .5rem;margin-top:.5rem}
.f .meta .chip{font-size:.58rem}
.f .meta .cite{font-family:var(--mono);font-size:.66rem;color:var(--muted)}
.f .meta .cite a{border-bottom:1px solid var(--line-strong)}
.f .meta .cite a:hover{color:var(--accent-deep);border-bottom-color:var(--accent)}
.legend-dir{display:flex;flex-wrap:wrap;gap:.5rem 1.3rem;margin-top:1.2rem;font-size:.84rem;color:var(--muted)}
.legend-dir span{display:inline-flex;align-items:center;gap:.45rem}
.legend-dir i{font-style:normal;width:1.4rem;height:1.4rem;border-radius:50%;display:inline-flex;align-items:center;justify-content:center;font-family:var(--serif);font-size:.85rem;border:1px solid var(--line-strong);background:var(--paper-2)}
.legend-dir i.up{border-color:var(--sand-line);background:var(--sand-soft);color:#7d5f2f}
.legend-dir i.down{border-color:var(--accent-line);background:var(--accent-soft);color:var(--accent-deep)}
.legend-dir i.same{border-style:dashed}

/* ---------- small data bars (PET vs autoradiography) ---------- */
.agree-mini{background:var(--card);border:1px solid var(--line);border-radius:var(--radius);padding:1.1rem 1.2rem}
.agree-mini .k{font-family:var(--mono);font-size:.62rem;letter-spacing:.16em;text-transform:uppercase;color:var(--muted)}
.agree-mini svg{width:100%;height:auto;display:block;margin-top:.6rem}
.agree-mini svg text{font-family:var(--sans);font-size:11px;fill:var(--ink-soft)}
.agree-mini svg .lab{font-family:var(--mono);font-size:9.5px;letter-spacing:.06em;fill:var(--muted)}
.agree-mini p{font-size:.9rem;color:var(--ink-soft);margin-top:.7rem}

/* ---------- figures with a real credit line ---------- */
.fig .frame.paper{background:var(--paper-2)}
.fig .frame a.zoom{display:block}
.fig-pair.wide-first{grid-template-columns:minmax(0,1.2fr) minmax(0,.8fr)}
@media (max-width:760px){.fig-pair.wide-first{grid-template-columns:1fr}}

/* ---------- where next ---------- */
.papers-more{margin-top:1.2rem;display:flex;flex-wrap:wrap;gap:.6rem 1.4rem;align-items:center;font-size:.92rem}
.papers-more a{font-family:var(--mono);font-size:.76rem;color:var(--accent-deep);border-bottom:1px solid var(--accent-line)}
.themes-band{border-top:1px solid var(--line);background:var(--paper)}
.themes-band .wrap{padding-block:clamp(2.6rem,6vw,4rem)}
.themes-band .eyebrow{margin-bottom:1.2rem}
.themes-grid{display:grid;grid-template-columns:repeat(4,minmax(0,1fr));gap:1px;background:var(--line);border:1px solid var(--line);border-radius:var(--radius);overflow:hidden}
@media (max-width:900px){.themes-grid{grid-template-columns:repeat(2,minmax(0,1fr))}}
@media (max-width:520px){.themes-grid{grid-template-columns:1fr}}
.themes-grid > a,.themes-grid > div{background:var(--paper-2);padding:1.3rem 1.2rem 1.2rem;display:flex;flex-direction:column;gap:.45rem;transition:background .25s ease}
.themes-grid > a:hover{background:var(--card)}
.themes-grid .n{font-family:var(--mono);font-size:.66rem;letter-spacing:.16em;color:var(--accent)}
.themes-grid .h{font-family:var(--serif);font-size:1.2rem;line-height:1.25;color:var(--ink)}
.themes-grid .d{font-size:.88rem;color:var(--muted);line-height:1.5}
.themes-grid .go{margin-top:auto;padding-top:.4rem;font-family:var(--mono);font-size:.7rem;color:var(--accent-deep)}
.themes-grid .here{background:var(--card);box-shadow:inset 0 3px 0 var(--accent)}
.themes-grid .here .go{color:var(--muted)}

.note .k{display:block}